Contrary to the Western view of civilization, which sees the family as an obstacle to the freedom and equality of human beings; From the perspective of Islam, the family is the cradle of human peace and spiritual residence in order to create the ground for human spiritual growth and excellence. Therefore, the strength of the family can facilitate the realization of this important issue, and its weakness will challenge the happiness of human beings in the hereafter. The main question of the present study is what are the most important factors in strengthening the family from Ayatollah Khamenei's point of view? To answer this question, the documentary method has been used in data collection and the content analysis method has been used for data analysis. According to the research findings, nine factors can be considered as the most important factors in family strength that each man and woman have a joint role in playing. These nine factors can be divided into three parts: premarital, postmarital, and common before and after marriage. Factors before marriage are: marriage at the right time, having the right motivation, having the right criteria, the factor before and after marriage is: recognizing differences, patterns and rights and factors after marriage are: religiosity, simplicity, love And love, loyalty and trust, compatibility and forgiveness. It seems that love and affection can be considered as the focal point of strengthening factors. It also seems that premarital factors are mainly cognitive and postmarital factors are mainly emotional.